How to unlock Vault in Reliquary Act 5 in Path of Exile. Guide to open vault, rewards, keys of Strength and Devotion location

TL;DR

  • Find Key of Strength and Key of Devotion in random Reliquary chests marked as quest items
  • Clear the vault area methodically while searching all containers for optimal efficiency
  • Expect rare items and currency from the central chest with moderate upgrade potential
  • Use the vault rewards to supplement your Act 5 gear progression
  • Understand how this content integrates with the Settlers of Kalguur league mechanics

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Path of Exile’s 3.25 update introduced an intriguing new obstacle within Act 5’s campaign progression. Adventurers exploring the Reliquary area will encounter a substantial secured chamber demanding two distinct keys for access. This guide provides comprehensive strategies for locating the necessary components and maximizing the benefits from this optional content.

The imposing vault entrance showcases a massive reinforced door featuring dual key receptacles, which veteran players may recognize from previous game iterations. These architectural elements previously appeared during the epilogue phase before narrative restructuring. Securing both the Key of Strength and Key of Devotion requires dedicated exploration, as they spawn randomly within various containers throughout the Reliquary zone.

Successfully acquiring both specialized keys demands a systematic search methodology. These essential items generate arbitrarily within the multitude of chests, crates, and containers scattered across the Reliquary location. To efficiently complete this objective, methodically investigate every potential loot source while advancing through the area. The game interface assists this process by clearly designating them as quest objectives on your mini-map and area overview.


Optimize your search pattern by clearing enemy clusters first, then thoroughly scanning the perimeter. New players often waste time by immediately rushing toward every container, which frequently results in unnecessary combat engagements. Instead, establish area control before dedicating attention to loot investigation. The keys typically appear within standard chest models rather than specialized containers, so prioritize these common variants during your exploration.

Upon gaining entry, the vault’s interior presents multiple hostile guardians protecting treasure accumulations that offer limited individual value. Positioned centrally within the chamber rests an elaborate chest that disburses numerous rare-grade equipment pieces alongside currency items. While these acquisitions can potentially enhance your character’s capabilities during the campaign, their overall impact remains moderate rather than game-changing.

The defensive creatures within typically consist of standard Reliquary adversaries rather than unique boss-type enemies. Focus on eliminating ranged combatants initially to minimize damage intake while clearing the area. The primary chest’s contents generally provide the most significant upgrade opportunities, particularly for characters progressing through Act 5 with suboptimal gear. For comprehensive equipment strategies, consult our Weapons Unlock guide for parallel principles.

Update 3.25 concurrently launched the innovative Settlers of Kalguur challenge league, introducing comprehensive settlement administration mechanics. This system incorporates resource extraction, agricultural development, and trade logistics components. The expansion delivers abundant new incentives and encounter varieties for both novice and experienced participants.

The vault mechanism functions independently from the league’s primary mechanics but provides supplemental resources that can accelerate your early settlement establishment. The acquired currency and vendor fodder can be leveraged to enhance your initial economic foundation. Understanding these synergies is crucial for optimal campaign progression, similar to mastering fundamentals in our Class Guide for role specialization.

For players engaged in the new league, consider delaying vault exploration until after establishing basic settlement infrastructure. The rewards become more impactful when you have crafting benches and vendor access available. This strategic timing parallels the importance of foundational knowledge in our Complete Guide to core game systems.

Action Checklist

  • Clear Reliquary area enemies before searching containers systematically
  • Check all standard chest types while watching for quest item markers on minimap
  • Prioritize ranged enemy elimination upon vault entry to minimize damage taken
  • Evaluate central chest rewards for potential gear upgrades during Act 5 progression
  • Integrate vault acquisitions into your Settlers of Kalguur league economic strategy

No reproduction without permission:Game Guides » How to unlock Vault in Reliquary Act 5 in Path of Exile. Guide to open vault, rewards, keys of Strength and Devotion location Master the Path of Exile Act 5 Vault with key locations, strategic tips, and reward optimization guide